What’s the S Curve?
Driving the S Curve for Pharma
The Earlier the Better
Our Recipe for a Successful Drive
Our Applied SmartFactory Rx® suite offers a proven, successful approach for improving quality, yield and productivity to help pharma manufacturers successfully drive the S curve and realize hidden potential. This approach touches on each of the critical stages moving through development to commercial scale manufacturing.
The optimized experimental design platform (OEDP) within our Smart Process Development solution accelerates product development and enables early-stage learnings to be transferred directly into control strategy development. This lays the foundation for confident scale-up to commercial manufacturing. Using Advanced Process Control (APC) and Model Predictive Control, we can manage process variability to optimize yield over time (see Figure 2). Throughout clinical manufacturing, inventory and just in time (JIT) supply can be a significant constraint. Our Smart Scheduling platform has been designed to help address these challenges. To read more about this capability click here.
Ramp – During this phase, we are aiming to reduce process variation, minimize waste, and optimize a stable yield. This has to be achieved while complying with the high-quality standards of pharma validation criteria.
Key to this approach is deploying software solutions to bring production reality closer to target (see Figure 3). Adaptive scheduling in response to changes on the shop floor, QC labs, and the wider supply chain can increase productivity by enabling the E2E coordination between operations, quality and supply chain. This aims to help pharma manufacturers resolve challenges throughout production, resulting in faster time to market, higher quality and less waste.
Summary
Today’s pharma manufacturing challenges are difficult regardless of the stage of pharma development or manufacturing and supply timelines you are in. Manufacturers are facing shorter and shorter product life cycles and rapidly eroding margins following many years of development. Whether you need to accelerate the tech transfer of a new process, or enhance the productivity of your installed base, our extensive software capabilities can help you “drive the S curve” to ensure that production reality meets your production goal. In this environment, SmartFactory Rx offers an E2E automation software suite designed for achieving yield, output, and cost improvements at every step of the drug life cycle.
